SEQUENCE DIVERSITY, LOCUS STRUCTURE, AND EVOLUTIONARY HISTORY OF THE SPTRANSFORMER GENES IN THE SEA URCHIN GENOME

Sequence Diversity, Locus Structure, and Evolutionary History of the SpTransformer Genes in the Sea Urchin Genome

The generation of large immune gene families is often driven by evolutionary pressure exerted on host genomes by Water Bottle their pathogens, which has been described as the immunological arms race.The SpTransformer (SpTrf) gene family from the California purple sea urchin, Strongylocentrotus purpuratus, is upregulated upon immune challenge and en

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Regional lymphadenectomy vs. extended lymphadenectomy for hilar cholangiocarcinoma (Relay-HC trial): study protocol for a prospective, multicenter, randomized controlled trial

Abstract Background The prognostic benefits and safety of extended lymphadenectomy for hilar cholangiocarcinoma remain uncertain.The available evidence is still insufficient concerning its retrospective aspect.The aim of this study is to explore the clinical effect and safety of extended lymphadenectomy compared to regional lymphadenectomy in patie

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Integrated manufacturing of direct 3D-printed clear aligners

The inception of laboratory work for the construction of a removable, tooth-moving appliance by sectioning teeth from the malocclusion model Asciugasmalto to align them with wax and achieve minor dental correction has evolved into a state of digital planning and appliance manufacturing for a wide spectrum of malocclusions.The groundbreaking technol

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Immunological Responses to Envenomation

Venoms are complex mixtures of toxic compounds delivered by bite or sting.In humans, the consequences of envenomation range from self-limiting to VOLUMIZING REFLECTIVES lethal.Critical host defence against envenomation comprises innate and adaptive immune strategies targeted towards venom detection, neutralisation, detoxification, and symptom resol

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